Description

(5-(4-Chlorophenyl)Thiophen-2-Yl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates for drug discovery and specialty chemical production.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic acid, critical for synthesizing complex biaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing chlorophenyl-thiophene scaffolds with potential biological activity.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides that require specific chlorinated aromatic heterocycles.
• Material Science & OLED Development: A precursor for synthesizing organic semiconductors, ligands for catalysts, and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and inhibitors for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up production for clients.

Basic Information

Item	Detail
Product Name	(5-(4-Chlorophenyl)Thiophen-2-Yl)Boronic Acid
CAS No.	1210470-48-6
Molecular Formula	C10H8BClO2S
Molecular Weight	238.50 g/mol
Synonyms	5-(4-Chlorophenyl)thiophene-2-boronic acid; [5-(4-Chlorophenyl)-2-thienyl]boronic acid; 2-(4-Chlorophenyl)thiophene-5-boronic acid; (5-(p-Chlorophenyl)thiophen-2-yl)boronic acid; 4-Chlorophenyl-2-thienylboronic acid; Boronic acid, B-[5-(4-chlorophenyl)-2-thienyl]-; 1210470-48-6
EINECS	Contact for details

Quality Control

Every batch of (5-(4-Chlorophenyl)Thiophen-2-Yl)Boronic Acid undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive cross-coupling applications. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality management and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.