Description

7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,2,4]Triazolo[1,5-A]Pyridine is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing fused triazolopyridine cores.
• Suzuki-Miyaura Cross-Coupling: Enables the efficient and selective introduction of the triazolopyridine moiety into complex molecules under mild palladium-catalyzed conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and inhibitors for studying biological pathways and target validation.
• Library Synthesis: A valuable reagent for generating diverse compound libraries in high-throughput screening and drug discovery campaigns.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,2,4]Triazolo[1,5-A]Pyridine
CAS No.	1210048-18-2
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine; [1,2,4]Triazolo[1,5-a]pyridine-7-boronic acid pinacol ester; 7-(Pinacolatoboryl)-[1,2,4]triazolo[1,5-a]pyridine; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,4-triazolo[1,5-a]pyridine; 7-Triazolopyridine boronic acid pinacol ester; Pinacol 7-([1,2,4]triazolo[1,5-a]pyridin-7-yl)boronate; 7-Borono-[1,2,4]triazolo[1,5-a]pyridine pinacol ester
EINECS	Contact for details

Quality Control

Our 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,2,4]Triazolo[1,5-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for extended shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.