Description

2-Amino-5-Bromo-3-Fluoro-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its unique halogenated and aminated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated benzonitrile core.
• Material Science Research: Serves as a precursor for functional dyes, liquid crystals, and organic electronic materials due to its electron-withdrawing nitrile group and halogen substituents.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring precise functionalization on a benzene ring.

Basic Information

Product Name	2-Amino-5-Bromo-3-Fluoro-Benzonitrile
CAS No.	1209498-46-3
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	5-Bromo-3-fluoro-2-aminobenzonitrile; 2-Amino-5-bromo-3-fluorobenzonitrile; Benzonitrile, 2-amino-5-bromo-3-fluoro-; 3-Fluoro-2-amino-5-bromobenzonitrile; 5-Bromo-2-amino-3-fluorobenzonitrile; 2-Amino-3-fluoro-5-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Fluoro-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.