Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoxalin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its role as a key synthon in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing quinoxaline and boron-substituted heterocycles.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic ester reagent for palladium-catalyzed carbon-carbon bond formation, essential for creating complex organic molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the biological activity of the quinoxaline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and emissive layer components in advanced display technologies.
• Material Science: Employed in the synthesis of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a probe or linker in bioconjugation chemistry and the development of enzyme inhibitors.

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoxalin-2(1H)-One
CAS No.	1209498-40-7
Molecular Formula	C₁₄H₁₇BN₂O₃
Molecular Weight	272.11 g/mol
Synonyms	2(1H)-Quinoxalinone, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydroquinoxalin-2-one; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxalin-2(1H)-one; 6-Pinacolboryl-1,2-dihydroquinoxalin-2-one; Quinoxalin-2(1H)-one, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoxalin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.