Description

1-(2,5-Difluorophenyl)-2-Methoxyethan-1-Amine Hydrochloride is a high-purity, fluorinated amine hydrochloride salt of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique difluorophenyl moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for exploring structure-activity relationships (SAR) and synthesizing fluorinated analogs of bioactive molecules.
• Material Science Precursor: Potential use in the synthesis of advanced polymers and functional materials with specific electronic or surface properties.

Basic Information

Product Name	1-(2,5-Difluorophenyl)-2-Methoxyethan-1-Amine Hydrochloride
CAS No.	1209410-63-8
Molecular Formula	C9H12ClF2NO
Molecular Weight	223.65 g/mol
Synonyms	1-(2,5-Difluorophenyl)-2-methoxyethanamine hydrochloride; 2,5-Difluoro-α-(methoxymethyl)benzylamine hydrochloride; 1-Amino-1-(2,5-difluorophenyl)-2-methoxyethane hydrochloride; (2,5-Difluorophenyl)(methoxymethyl)methylamine hydrochloride; α-Methoxy-2,5-difluorobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 1-(2,5-Difluorophenyl)-2-Methoxyethan-1-Amine Hydrochloride is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.