Description

1-(2-Fluoro-6-Methoxyphenyl)-2,2,2-Trifluoroethan-1-One, also known as 3-Fluoro-2-(Trifluoroacetyl)Anisole, is a high-value fluorinated aromatic ketone building block essential for advanced organic synthesis. Its unique structure, featuring both methoxy and trifluoroacetyl groups on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors and liquid crystals for electronic applications.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom chemical synthesis services targeting niche and proprietary compounds.

Basic Information

Item	Details
Product Name	1-(2-Fluoro-6-Methoxyphenyl)-2,2,2-Trifluoroethan-1-One, 3-Fluoro-2-(Trifluoroacetyl)Anisole
CAS No.	1208078-28-7
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	3-Fluoro-2-(trifluoroacetyl)anisole; 1-(2-Fluoro-6-methoxyphenyl)-2,2,2-trifluoroethanone; 2-Fluoro-6-methoxy-α,α,α-trifluoroacetophenone; 2'-Fluoro-6'-methoxy-2,2,2-trifluoroacetophenone; α,α,α-Trifluoro-2-fluoro-6-methoxyacetophenone; 2,2,2-Trifluoro-1-(2-fluoro-6-methoxyphenyl)ethanone; 1-(2-Fluoro-6-methoxyphenyl)-2,2,2-trifluoro-1-ethanone
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-6-Methoxyphenyl)-2,2,2-Trifluoroethan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.