Description

4-Chloro-2,6-Difluorobenzenesulfonylchloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated aromatic structure. This compound matters for its critical role as a versatile building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfonamide-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides with sulfonylurea or sulfonamide moieties.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Research: A versatile reagent in organic synthesis for introducing the sulfonyl chloride functional group into complex molecules.
• Dye & Pigment Industry: Intermediate in the manufacture of specialized colorants and photographic chemicals.
• Ligand Synthesis: Used for creating specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-2,6-Difluorobenzenesulfonylchloride
CAS No.	1208077-94-4
Molecular Formula	C6H2Cl2F2O2S
Molecular Weight	247.04 g/mol
Synonyms	2,6-Difluoro-4-chlorobenzenesulfonyl chloride; 4-Chloro-2,6-difluorobenzene-1-sulfonyl chloride; 1-Chloro-3,5-difluoro-4-sulfonylchloridebenzene; Benzenesulfonyl chloride, 4-chloro-2,6-difluoro-; 4-Chloro-2,6-difluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,6-Difluorobenzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.