Description

2-(4-Chloro-2-Methoxy-6-Methyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is critical for enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to modern drug discovery and materials science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to construct complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron reagent for forming carbon-carbon bonds between aromatic rings, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Acts as a precursor in the synthesis of complex ligands and organometallic catalysts.
• Chemical Biology & Proteomics: Can be used as a tagging or labeling reagent for bioconjugation and probe development.

Basic Information

Product Name	2-(4-Chloro-2-Methoxy-6-Methyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	1207961-49-6
Molecular Formula	C14H20BClO3
Molecular Weight	282.57 g/mol
Synonyms	4-Chloro-2-methoxy-6-methylbenzeneboronic acid pinacol ester; (4-Chloro-2-methoxy-6-methylphenyl)boronic acid pinacol ester; 2-(4-Chloro-2-methoxy-6-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-2-methoxy-6-methylphenylboronic acid pinacol ester; Pinacol (4-chloro-2-methoxy-6-methylphenyl)boronate; CAS 1207961-49-6; B-(4-Chloro-2-methoxy-6-methylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-2-Methoxy-6-Methyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.