Description

6-(Hydroxymethyl)Pyridin-2-Yl-2-Boronic Acid is a high-value boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its bifunctional structure, featuring both a boronic acid and a hydroxymethyl group on a pyridine scaffold, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is primarily used in Suzuki-Miyaura cross-coupling reactions to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct novel heterocyclic compounds for crop protection agents and herbicides.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Ligand Synthesis: Serves as a starting material for creating sophisticated bidentate and tridentate ligands in catalysis.
• Bioconjugation: Utilized in the development of probes and linkers for bioconjugation chemistry and diagnostic applications.
• Chemical Library Development: A valuable building block for generating diverse compound libraries in drug discovery and high-throughput screening.

Basic Information

Product Name	6-(Hydroxymethyl)Pyridin-2-Yl-2-Boronic Acid
CAS No.	1207749-62-9
Molecular Formula	C6H8BNO3
Molecular Weight	152.95 g/mol
Synonyms	2-(6-(Hydroxymethyl)pyridin-2-yl)boronic acid; (6-(Hydroxymethyl)pyridin-2-yl)boronic acid; 2-Borono-6-(hydroxymethyl)pyridine; 6-(Hydroxymethyl)-2-pyridineboronic acid; 2-Pyridineboronic acid, 6-(hydroxymethyl)-; 6-Hydroxymethylpyridine-2-boronic acid; PINAP-B(OH)2 derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 6-(Hydroxymethyl)Pyridin-2-Yl-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability, as boronic acids can be sensitive to prolonged air exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.