Description

Benzoic Acid, 4-Borono-2-Hydroxy-, 1-Methyl Ester is a specialized boronic acid ester derivative of benzoic acid, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a boronate ester functional group with a phenolic hydroxyl, making it a versatile intermediate for cross-coupling reactions and pharmaceutical development. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions to form biaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the boronic acid ester moiety facilitates the creation of complex bioactive molecules.
• Material Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of advanced polymers, sensors, and boron-containing materials.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in the development of chemical probes, enzyme inhibitors, and bioconjugation strategies.
• Organic Synthesis Reagent: Utilized as a versatile building block for constructing complex organic molecules in academic and industrial research laboratories.

Basic Information

Product Name	Benzoic Acid, 4-Borono-2-Hydroxy-, 1-Methyl Ester
CAS No.	1207726-24-6
Molecular Formula	C9H11BO4
Molecular Weight	193.99 g/mol
Synonyms	4-(Methoxycarbonyl)-3-hydroxybenzeneboronic acid; Methyl 4-borono-2-hydroxybenzoate; 2-Hydroxy-4-(methoxycarbonyl)benzeneboronic acid; 4-Carbomethoxy-2-hydroxybenzeneboronic acid; Methyl 2-hydroxy-4-boronobenzoate; 4-(Methoxycarbonyl)-2-hydroxybenzeneboronic acid; Boronic acid, B-[4-(methoxycarbonyl)-2-hydroxyphenyl]-; 1207726-24-6
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Borono-2-Hydroxy-, 1-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.