Description

4-Methyl-7-Azaindole-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling characteristics for critical cross-coupling reactions. This compound is essential for researchers and manufacturers in medicinal chemistry, particularly for the development of novel small-molecule therapeutics and agrochemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds in drug discovery programs.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science: A precursor for creating organic electronic materials and functional polymers via palladium-catalyzed polymerization.
• Chemical Biology & Probe Development: Enables the synthesis of molecular probes for studying biological processes and enzyme functions.
• Library Synthesis for High-Throughput Screening: Facilitates the rapid generation of diverse compound libraries for lead identification and optimization.

Basic Information

Product Name	4-Methyl-7-Azaindole-5-Boronic Acid Pinacol Ester
CAS No.	1207626-84-3
Molecular Formula	C14H19BN2O2
Molecular Weight	258.13 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-7-azaindole; 4-Methyl-1H-pyrrolo[2,3-b]pyridine-5-boronic acid pinacol ester; 4-Methyl-7-azaindol-5-ylboronic acid pinacol ester; 4-Methyl-1H-pyrrolo[2,3-b]pyridin-5-ylboronic acid, pinacol ester; 4-Methyl-7-aza-indole-5-boronic acid pinacol ester; 4-Methyl-1H-pyrrolo[2,3-b]pyridine-5-boronic acid, 1,1-dimethylethyl ester (Pinacol Ester)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Each batch is characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We adhere to cGMP principles for manufacturing critical intermediates, supporting our commitment to supply chain reliability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.