Description

Ethyl2-(3-Fluoro-6-Methoxy-1,5-Naphthyridin-4-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D labs.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for preclinical and clinical trial material production.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals due to its heterocyclic structure.

Basic Information

Product Name	Ethyl2-(3-Fluoro-6-Methoxy-1,5-Naphthyridin-4-Yl)Acetate
CAS No.	1207621-43-9
Molecular Formula	C₁₃H₁₃FN₂O₃
Molecular Weight	264.25 g/mol
Synonyms	Ethyl (3-Fluoro-6-methoxy-1,5-naphthyridin-4-yl)acetate; 4-(2-Ethoxy-2-oxoethyl)-3-fluoro-6-methoxy-1,5-naphthyridine; 1,5-Naphthyridine, 4-(2-ethoxy-2-oxoethyl)-3-fluoro-6-methoxy-; Ethyl 2-(3-Fluoro-6-methoxy-1,5-naphthyridin-4-yl)acetate; 1207621-43-9; 3-Fluoro-6-methoxy-1,5-naphthyridin-4-ylacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl2-(3-Fluoro-6-Methoxy-1,5-Naphthyridin-4-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.