Description

Ethyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by pharmaceutical, agrochemical, and advanced materials research and development teams for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between thiophene derivatives and aryl/heteroaryl halides.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiophene or biaryl motifs.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced properties.
• Organic Electronic Materials: A precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological processes.

Basic Information

Product Name	Ethyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate
CAS No.	1207557-61-6
Molecular Formula	C13H19BO4S
Molecular Weight	282.16 g/mol
Synonyms	Ethyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; Ethyl 4-(pinacolatoboran-2-yl)thiophene-2-carboxylate; 4-(Pinacolatoboryl)thiophene-2-carboxylic acid ethyl ester; Ethyl 4-(pinacolboronato)thiophene-2-carboxylate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylic acid ethyl ester; 1207557-61-6
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.