Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazolo[1,5-A]Pyridine CAS NO 1207557-48-9 is a high-value, heterocyclic boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used to construct complex molecular scaffolds for novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, due to its conjugated pyrazolopyridine core.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry approaches.
• Ligand Synthesis for Catalysis: Can be utilized to create novel bidentate or polydentate ligands for transition metal catalysis.

Basic Information

Item	Details
Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazolo[1,5-A]Pyridine
CAS No.	1207557-48-9
Molecular Formula	C15H19BN2O2
Molecular Weight	270.14 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine; Pyrazolo[1,5-a]pyridine-3-boronic acid pinacol ester; 3-Pinacolatoborylpyrazolo[1,5-a]pyridine; 3-(Pyrazolo[1,5-a]pyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1207557-48-9; Pyrazolo[1,5-a]pyridine-3-boronic acid, pinacol ester; Boronic acid, B-(pyrazolo[1,5-a]pyridin-3-yl)-, pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazolo[1,5-A]Pyridine is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR (1H, 13C, 11B), and GC/MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.