Description

5,5-Difluoro-1-Methyl-7-Oxa-Bicyclo[4.1.0]Heptane is a high-value, fluorinated oxabicycloheptane derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique strained bicyclic structure, functionalized with fluorine atoms, makes it an indispensable building block for introducing conformational rigidity and fluorinated motifs into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorinated bicyclic core can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials that benefit from its rigid, fluorinated structure.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating fluorinated probes and tags used in bioimaging and mechanistic studies.
• Catalyst and Ligand Design: Acts as a precursor for chiral auxiliaries or ligands in asymmetric catalysis, leveraging its three-dimensional architecture.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in ring-opening and functionalization reactions.

Basic Information

Product Name	5,5-Difluoro-1-Methyl-7-Oxa-Bicyclo[4.1.0]Heptane
CAS No.	1207557-25-2
Molecular Formula	C7H10F2O
Molecular Weight	148.15 g/mol
Synonyms	1-Methyl-5,5-difluoro-7-oxabicyclo[4.1.0]heptane; 5,5-Difluoro-1-methyl-7-oxabicyclo[4.1.0]heptane; 1-Methyl-5,5-difluorooxepane (incorrect but common search); Difluoromethyl oxabicycloheptane; 7-Oxa-bicyclo[4.1.0]heptane, 5,5-difluoro-1-methyl-; Fluorinated oxabicycloheptane intermediate
EINECS	Contact for details

Quality Control

Every batch of 5,5-Difluoro-1-Methyl-7-Oxa-Bicyclo[4.1.0]Heptane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for advanced R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride ions; ensure it is stored separately from such materials. For long-term storage, consider keeping the container under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.