Description

[((R)-Dtbsiphox)Ir(Cod)]Barf is a highly specialized, chiral iridium-based organometallic catalyst. This compound is valued for its exceptional enantioselectivity and catalytic efficiency in asymmetric hydrogenation and other transition metal-catalyzed reactions. It is a critical reagent for research and development in advanced pharmaceutical synthesis and fine chemical manufacturing, enabling the production of single-enantiomer intermediates.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Chiral Ligand Complex: Serves as a pre-formed catalyst for C-H activation and C-C bond-forming reactions under mild conditions.
• Pharmaceutical R&D: Key tool in the discovery and process development of active pharmaceutical ingredients (APIs) requiring high optical purity.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where stereochemical control is paramount.
• Academic & Industrial Research: A benchmark catalyst for methodological studies in organometallic chemistry and catalysis.

Basic Information

Product Name	[((R)-Dtbsiphox)Ir(Cod)]Barf
CAS No.	1207473-29-7
Molecular Formula	C₄₇H₆₀BF₂₀IrOP
Molecular Weight	1384.76 g/mol
Synonyms	(R)-DTBS-IPHOX Iridium(I) (1,5-Cyclooctadiene) Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; Iridium(I)-(R)-DTBS-IPHOX-(1,5-cyclooctadiene) BARF Salt; (R)-3,5-di-tert-Butyl-4-methoxyphenylmethylphosphine-Iridium-COD BARF Complex; [Ir((R)-Dtbsiphox)(cod)]BArF; Chiral Iridium-Dtbsiphox Catalyst; Iridium(I) (1,5-cyclooctadiene) (R)-DTBS-IPHOX BArF Salt
EINECS	Contact for details

Quality Control

Every batch of [((R)-Dtbsiphox)Ir(Cod)]Barf is manufactured and handled under inert atmosphere to preserve its catalytic activity. It undergoes rigorous analytical characterization, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and enantiomeric excess meet stringent research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a freezer. This compound is easily oxidized and strictly light-sensitive; prolonged exposure to air, moisture, or light will degrade its catalytic performance. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Enantiomeric Purity	≥ 99% ee
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.