Description

2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One is a high-purity, heterocyclic organoboron building block essential for modern synthetic chemistry. This compound matters as a versatile intermediate in the development of novel pharmaceuticals and advanced materials, enabling key cross-coupling and functionalization reactions. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing coupling partner for constructing complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new herbicides and fungicides with novel modes of action.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and inhibitors for studying biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One
CAS No.	1207448-46-1
Molecular Formula	C₁₃H₁₂BNO₃
Molecular Weight	241.05 g/mol
Synonyms	1(2H)-Isoquinolinone, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1(2H)-one; 2-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-isoquinolinone; 1-Oxo-1,2-dihydroisoquinoline-2-boronic acid pinacol ester; Isoquinolin-1(2H)-one, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.