Description

2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One is a high-value, heterocyclic organoboron compound that serves as a critical synthetic intermediate. Its unique structure, featuring a fused isoquinolinone core with a dioxaborolane protecting group, makes it an essential building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced materials chemists for applications in medicinal chemistry, catalyst development, and the synthesis of functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, protected boronic ester reagent for palladium-catalyzed carbon-carbon bond formation, enabling the construction of biaryl structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific heterocyclic scaffolds.
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its planar conjugated system is advantageous.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and sensors due to its reactive handle for further functionalization.
• Academic & Contract Research: Essential reagent for methodology development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One
CAS No.	1207448-16-5
Molecular Formula	C₁₃H₁₂BNO₃
Molecular Weight	241.05 g/mol
Synonyms	1(2H)-Isoquinolinone, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1(2H)-one; 2-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1(2H)-isoquinolinone; Pinacol (1-oxo-1,2-dihydroisoquinolin-2-yl)boronate; 1-Oxo-1,2-dihydroisoquinoline-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced spectroscopic and chromatographic techniques, including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.