Description

1-(3-Chloro-5-Nitrophenyl)Ethanone is a high-purity, specialized aromatic ketone building block of significant importance in advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals, polymers, and organic semiconductors.
• Dye and Pigment Intermediate: Functions as a starting material for synthesizing specialized azo dyes and nitro-aromatic pigments.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the presence of reactive halogen and nitro groups.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and exploring new synthetic pathways.

Basic Information

Item	Details
Product Name	1-(3-Chloro-5-Nitrophenyl)Ethanone
CAS No.	1207175-00-5
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	3'-Chloro-5'-nitroacetophenone; 1-Acetyl-3-chloro-5-nitrobenzene; 3-Chloro-5-nitroacetophenone; Ethanone, 1-(3-chloro-5-nitrophenyl)-; (3-Chloro-5-nitrophenyl)ethan-1-one; 1-(3-Chloro-5-nitrophenyl)ethanone; 3-Chloro-5-nitroacetylbenzene; Acetophenone, 3'-chloro-5'-nitro-
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Chloro-5-Nitrophenyl)Ethanone is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.