Description

Methyl 2',3'-Dichloro-5-Methyl-3-Oxo-1,2,3,6-Tetrahydro-[1,1'-Biphenyl]-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides or fungicides with specific modes of action.
• Chemical Synthesis Building Block: Used in organic chemistry research for constructing complex polycyclic frameworks and exploring novel reaction pathways.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale production runs for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Methyl 2',3'-Dichloro-5-Methyl-3-Oxo-1,2,3,6-Tetrahydro-[1,1'-Biphenyl]-2-Carboxylate
CAS No.	1207068-15-2
Molecular Formula	C16H16Cl2O3
Molecular Weight	327.20 g/mol
Synonyms	Methyl 2',3'-dichloro-5-methyl-3-oxo-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate; 2',3'-Dichloro-5-methyl-3-oxo-1,2,3,6-tetrahydrobiphenyl-2-carboxylic acid methyl ester; 1,2,3,6-Tetrahydro-2',3'-dichloro-5-methyl-3-oxobiphenyl-2-carboxylic acid methyl ester; Bicyclo[3.2.1]octane derivative; CAS 1207068-15-2
EINECS	Contact for details

Quality Control

Our production of Methyl 2',3'-Dichloro-5-Methyl-3-Oxo-1,2,3,6-Tetrahydro-[1,1'-Biphenyl]-2-Carboxylate adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure consistency and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.