Description

4-[2-Hydroxyethyl(Methyl)Amino]Benzeneboronic Acid Pinacol Ester, 95% is a high-purity, organoboron building block essential for modern synthetic chemistry. Its value lies in its role as a protected boronic acid derivative, offering enhanced stability and solubility for cross-coupling reactions compared to its free acid form. This compound is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, enabling the efficient synthesis of complex molecules. The CAS number for this product is 1206641-45-3.

Application

This versatile boronic ester is a key reagent in advanced organic synthesis, primarily serving as a coupling partner in cross-coupling methodologies.

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for constructing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs) and functional materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Product Development: Employed in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Organic Electronic Materials: A component in the synthesis of conjugated polymers and small molecules for OLEDs, OFETs, and solar cells.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.

Basic Information

Item	Details
Product Name	4-[2-Hydroxyethyl(Methyl)Amino]Benzeneboronic Acid Pinacol Ester, 95%
CAS No.	1206641-45-3
Molecular Formula	C16H26BNO3
Molecular Weight	291.20 g/mol
Synonyms	4-[N-Methyl-N-(2-hydroxyethyl)amino]benzeneboronic acid pinacol ester; 4-[(2-Hydroxyethyl)(methyl)amino]phenylboronic acid pinacol ester; N-Methyl-N-(2-hydroxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; B-[4-[Methyl(2-hydroxyethyl)amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1206641-45-3; Boronic acid, B-[4-[methyl(2-hydroxyethyl)amino]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-[2-Hydroxyethyl(Methyl)Amino]Benzeneboronic Acid Pinacol Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.