Description

1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Cyclopropanecarbonitrile is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound matters for its role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical boron-containing reagent for forming carbon-carbon bonds between aryl and vinyl groups.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Acts as a precursor for bioconjugation and labeling reagents used in proteomics and diagnostics.
• Academic & Industrial R&D: A versatile tool for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Cyclopropanecarbonitrile
CAS No.	1206641-31-7
Molecular Formula	C16H20BNO2
Molecular Weight	269.15 g/mol
Synonyms	4-(Cyclopropylcarbonitrile)phenylboronic acid pinacol ester; 4-(Cyclopropanecarbonitrile)phenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarbonitrile; 4-(Cyclopropylcarbonitrile)benzeneboronic acid pinacol ester; 4-(Cyclopropanecarbonitrile)benzeneboronic acid pinacol ester; 4-(Cyclopropylcarbonitrile)phenylboronic acid, pinacol ester; 4-(Cyclopropanecarbonitrile)phenylboronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.