Description

3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Propan-1-Ol is a high-value, protected boronic ester derivative featuring a terminal hydroxyl group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for the synthesis of complex molecules via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring aryl-boronate coupling steps.
• Material Science & OLEDs: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other advanced functional polymers.
• Cross-Coupling Reactions: An essential reagent for Suzuki-Miyaura cross-coupling, enabling the formation of carbon-carbon bonds between aryl/vinyl groups.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Used to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Item	Details
Product Name	3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Propan-1-Ol
CAS No.	1206641-20-4
Molecular Formula	C15H23BO4
Molecular Weight	278.15 g/mol
Synonyms	3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)propan-1-ol; 4-(3-Hydroxypropoxy)phenylboronic acid pinacol ester; 3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-1-propanol; 4-(3-Hydroxypropoxy)benzeneboronic acid pinacol ester; 2-[4-(3-Hydroxypropoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.