Description

2',6'-Difluoro-3'-Methoxyacetophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical sector. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluoro-methoxy motif confers specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals for electronic and optical applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring fluorinated aromatic scaffolds.

Basic Information

Product Name	2',6'-Difluoro-3'-Methoxyacetophenone
CAS No.	1206593-23-8
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	1-(2,6-Difluoro-3-methoxyphenyl)ethan-1-one; 2,6-Difluoro-3-methoxyacetophenone; 3'-Methoxy-2',6'-difluoroacetophenone; Ethanone, 1-(2,6-difluoro-3-methoxyphenyl)-; Difluoro Methoxy Acetophenone
EINECS	Contact for details

Quality Control

Every batch of 2',6'-Difluoro-3'-Methoxyacetophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.