Description

2-Bromo-8-Iododibenzothiophene is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique dibenzothiophene core functionalized with distinct bromo and iodo substituents makes it a versatile precursor for constructing complex molecular architectures via selective cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the dibenzothiophene scaffold can contribute to unique biological activity.
• Materials Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of organic semiconductors, conductive polymers, and luminescent materials for OLEDs and electronic devices.
• Cross-Coupling Reactions: The differentiated halogen atoms (Br and I) allow for sequential, site-selective Suzuki, Stille, or Sonogashira cross-coupling reactions to create complex, polyfunctionalized molecules.
• Ligand Synthesis: Utilized for preparing novel chelating ligands for catalysis or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry and for exploring new chemical space in discovery research.

Basic Information

Product Name	2-Bromo-8-Iododibenzothiophene
CAS No.	1206544-88-8
Molecular Formula	C12H6BrIS
Molecular Weight	404.05 g/mol
Synonyms	Dibenzothiophene, 2-bromo-8-iodo-; 8-Iodo-2-bromodibenzothiophene; 2-Bromo-8-iodo-dibenzothiophene; 1206544-88-8; AI3-28635; SCHEMBL21842227; ZINC000095909966; AKOS040759215
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-8-Iododibenzothiophene is manufactured under a strict quality management system and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our standard research-grade material typically meets a high purity specification suitable for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results from NMR (1H, 13C), HPLC, and mass spectrometry analyses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.