Description

3-Amino-6-Chloropicolinaldehyde is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive aldehyde and amino functional groups. It is primarily sought after by R&D chemists and process development scientists for constructing novel active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized for synthesizing molecular probes and tags for biochemical research.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	3-Amino-6-Chloropicolinaldehyde
CAS No.	1206454-49-0
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	6-Chloro-3-aminopicolinaldehyde; 2-Amino-5-chloro-4-pyridinecarboxaldehyde; 5-Chloro-3-pyridinylcarboxaldehyde, 2-amino-; 3-Amino-6-chloro-2-pyridinecarboxaldehyde; 3-Amino-6-chloropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 3-amino-6-chloro-; 6-Chloro-3-aminopyridine-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Chloropicolinaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized and light-sensitive; minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.