Description

1-Benzyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indole is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of new active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create complex, bioactive molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for diagnostic and research applications.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	1-Benzyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indole
CAS No.	1206163-56-5
Molecular Formula	C21H24BNO2
Molecular Weight	333.24 g/mol
Synonyms	1-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzyl-1H-indole; 1-Benzyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)indole; 1-Benzylindole-5-boronic acid pinacol ester; 1-Benzyl-1H-indole-5-boronic acid pinacol ester; 5-Borono-1-benzylindole pinacol ester; B-(1-Benzyl-1H-indol-5-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-Benzyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Indole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive applications. All materials are fully characterized using advanced analytical techniques, including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.