Description

n-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for the development of active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific aryl-aryl bond formations.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of bioconjugation reagents and molecular probes for studying biological systems.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and catalysis studies.
• Liquid Crystal & Polymer Chemistry: Used to introduce functionalized aromatic units into polymers and liquid crystal molecules to modify their properties.

Basic Information

Product Name	n-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
CAS No.	1204742-78-8
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methoxybenzamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzohydroxamic acid methyl ester; 4-(Pinacolatoboryl)-N-methoxybenzamide; 4-Methoxyaminocarbonylphenylboronic acid pinacol ester; Benzamide, N-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1204742-78-8; Pinacol 4-(N-methoxycarbamoyl)phenylboronate
EINECS	Contact for details

Quality Control

Our n-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality assurance ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.