Description

4-Chloropyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical for synthesizing novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology & Diagnostics: Employed in the synthesis of molecular probes, sensors, and bioconjugates for research and diagnostic applications.
• Catalyst Ligand Development: Utilized to construct novel bidentate or polydentate ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	4-Chloropyridine-2-Boronic Acid Pinacol Ester
CAS No.	1204600-17-8
Molecular Formula	C11H15BClNO2
Molecular Weight	239.51 g/mol
Synonyms	4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4-Chloropyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-Chloropyridin-2-yl)boronic acid pinacol ester; 4-Chloro-2-pyridinylboronic acid pinacol ester; 4-Chloro-2-(pinacolatoboryl)pyridine; 1204600-17-8; 4-Chloropyridine-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Chloropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.