Description

2-Cyclohexylmethoxy-6-Methoxyphenylboronic Acid Pinacol Ester is a sophisticated arylboronic ester derivative, a crucial protected boronic acid building block for modern synthetic chemistry. Its primary value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and advanced material science, where it facilitates the creation of novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the construction of organic electronic materials, such as those for OLEDs and organic photovoltaics, where conjugated systems are critical.
• Chemical Biology Probes: Useful in the synthesis of molecular probes and tags for studying biological processes.
• Scalable Process Chemistry: The pinacol ester group enhances stability, making this reagent suitable for multi-step synthesis and potential scale-up in kilo-lab and pilot plant settings.

Basic Information

Product Name	2-Cyclohexylmethoxy-6-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1204580-87-9
Molecular Formula	C₂₀H₃₁BO₄
Molecular Weight	346.27 g/mol
Synonyms	[2-(Cyclohexylmethoxy)-6-methoxyphenyl]boronic acid pinacol ester; 2-(Cyclohexylmethoxy)-6-methoxybenzeneboronic acid pinacol ester; Pinacol [2-(cyclohexylmethoxy)-6-methoxyphenyl]boronate; B-[2-(Cyclohexylmethoxy)-6-methoxyphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Cyclohexylmethoxy-6-methoxybenzeneboronic acid pinacol ester; Boronic acid, B-[2-(cyclohexylmethoxy)-6-methoxyphenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Cyclohexylmethoxy-6-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Optimal storage temperature is 2-8°C (refrigerated). Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.