Description

2-Cyclobutylmethoxy-6-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, advanced boronic ester building block crucial for modern synthetic chemistry. Its core value lies in enabling efficient and selective cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, catalyst development, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage its boronic ester functionality for molecular diversification.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Catalyst Ligand Development: Employed in the design and synthesis of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tools for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Item	Details
Product Name	2-Cyclobutylmethoxy-6-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1204580-86-8
Molecular Formula	C18H27BO4
Molecular Weight	318.22 g/mol
Synonyms	2-(Cyclobutylmethoxy)-6-methoxyphenylboronic acid pinacol ester; (2-(Cyclobutylmethoxy)-6-methoxyphenyl)boronic acid pinacol ester; 2-Cyclobutylmethoxy-6-methoxybenzeneboronic acid pinacol ester; B-[2-(Cyclobutylmethoxy)-6-methoxyphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-(cyclobutylmethoxy)-6-methoxyphenyl)boronate; CAS 1204580-86-8
EINECS	Contact for details

Quality Control

Our 2-Cyclobutylmethoxy-6-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.