Description

(R)-1,1,1-Trifluoro-3-[(4-Methoxybenzyl)Oxy]-2-Propanol CAS NO 1204344-00-2 is a high-purity chiral fluorinated building block essential for advanced organic synthesis. This compound is valued for its trifluoromethyl group and protected alcohol functionality, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas like enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a specialized building block for fluorinated components in electronic display and lighting technologies.
• Asymmetric Catalysis & Ligand Development: Employed in the synthesis of novel chiral ligands and catalysts for stereoselective transformations.
• Fluorine-Containing Polymer Research: Acts as a monomer or modifier in the development of specialty polymers with unique surface properties and chemical resistance.
• Diagnostic & Imaging Agent Development: Utilized in the synthesis of probes and contrast agents that leverage the properties of fluorine-19 for NMR/MRI applications.

Basic Information

Product Name	(R)-1,1,1-Trifluoro-3-[(4-Methoxybenzyl)Oxy]-2-Propanol
CAS No.	1204344-00-2
Molecular Formula	C12H13F3O3
Molecular Weight	262.22 g/mol
Synonyms	(R)-1,1,1-Trifluoro-3-[(4-Methoxybenzyl)oxy]propan-2-ol; (R)-3-[(4-Methoxybenzyl)oxy]-1,1,1-trifluoropropan-2-ol; (R)-1,1,1-Trifluoro-3-(4-methoxybenzyloxy)-2-propanol; (R)-TFMOP; (R)-Trifluoromethyl PMB-protected glycerol; (R)-O-(4-Methoxybenzyl)-1,1,1-trifluoroisopropanol; (R)-1,1,1-Trifluoro-3-(p-methoxybenzyloxy)-2-propanol
EINECS	Contact for details

Quality Control

Our (R)-1,1,1-Trifluoro-3-[(4-Methoxybenzyl)Oxy]-2-Propanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.