Description

7-(Difluoromethyl)-1H-Indazole is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the difluoromethyl group attached to the indazole scaffold, making it a critical intermediate for developing novel compounds. This specialty chemical is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating new active ingredients with enhanced metabolic stability and bioavailability.

Application

• As a versatile pharmaceutical intermediate in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Utilized in agrochemical research for constructing novel herbicides, fungicides, and insecticides with improved efficacy.
• Serves as a key building block in material science for developing advanced organic electronic materials and functional polymers.
• Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Used as a specialty reagent in fluorine chemistry research to introduce the difluoromethyl motif into complex molecules.
• Acts as a precursor for the development of biochemical probes and diagnostic agents.

Basic Information

Product Name	7-(Difluoromethyl)-1H-Indazole
CAS No.	1204298-72-5
Molecular Formula	C8H6F2N2
Molecular Weight	168.15 g/mol
Synonyms	7-(Difluoromethyl)-1H-indazole; 1H-Indazole, 7-(difluoromethyl)-; 7-Difluoromethyl-1H-indazole; 7-(Difluoromethyl)indazole; 1204298-72-5; 7-(Difluoromethyl)indazole; 7-Difluoromethylindazole
EINECS	Contact for details

Quality Control

Our 7-(Difluoromethyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.