Description

4-(1,1-Difluoroethyl)-m-Xylene is a specialized fluorinated aromatic compound, serving as a high-value intermediate in advanced chemical synthesis. Its unique structure, featuring a difluoroethyl group on a meta-xylene backbone, makes it a critical building block for introducing fluorine atoms into complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise fluorination to modulate the biological activity, metabolic stability, and lipophilicity of their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display technologies, improving dielectric properties and thermal stability.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique properties such as chemical resistance, low surface energy, and improved weatherability.
• Organic Synthesis & Chemical Research: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and creating complex molecular architectures.

Basic Information

Product Name	4-(1,1-Difluoroethyl)-m-Xylene
CAS No.	1204295-93-1
Molecular Formula	C10H12F2
Molecular Weight	170.20 g/mol
Synonyms	1-(3,5-Dimethylphenyl)-1,1-difluoroethane; m-Xylene, 4-(1,1-difluoroethyl)-; 1,1-Difluoro-1-(3,5-dimethylphenyl)ethane; 3,5-Dimethyl-α,α-difluorotoluene; α,α-Difluoro-3,5-dimethyltoluene; 4-(Difluoroethyl)-1,3-dimethylbenzene
EINECS	Contact for details

Quality Control

Our 4-(1,1-Difluoroethyl)-m-Xylene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material standards, including cGMP manufacturing for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% (Total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.