Description

2,4,5-Trifluoro-n-Methyl-Benzamide is a high-purity fluorinated benzamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the trifluoro substitution pattern, which is essential for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by specialty chemical manufacturers producing advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance lipophilicity, metabolic stability, and binding affinity.
• Material Science Research: Employed as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its ability to influence molecular packing and electronic properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, enzyme inhibitors, and labeling reagents in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2,4,5-Trifluoro-n-Methyl-Benzamide
CAS No.	1203954-79-3
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	N-Methyl-2,4,5-trifluorobenzamide; 2,4,5-Trifluoro-N-methylbenzamide; Benzamide, 2,4,5-trifluoro-N-methyl-; 2,4,5-Trifluorobenzamide, N-methyl-; 1203954-79-3; N-Methyl-2,4,5-trifluorobenzamide; 2,4,5-Trifluoro-N-methyl-benzamide
EINECS	Contact for details

Quality Control

Every batch of 2,4,5-Trifluoro-n-Methyl-Benzamide is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable consistency and traceability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.