Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-1,2,3-Triazole is a versatile and high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable intermediates for drug discovery, ligand synthesis, and polymer development. CAS No. 1203672-88-1.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing triazole and boron-based pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science & Polymer Chemistry: Building block for creating functional polymers, metal-organic frameworks (MOFs), and advanced materials with tailored properties.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and coordination chemistry.
• Chemical Biology & Bioconjugation: Employed in probe and linker synthesis for labeling biomolecules and studying biological processes.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-1,2,3-Triazole
CAS No.	1203672-88-1
Molecular Formula	C9H16BN3O2
Molecular Weight	209.06 g/mol
Synonyms	1H-1,2,3-Triazole, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole; 1H-1,2,3-Triazol-5-ylboronic acid pinacol ester; 5-(Pinacolatoboryl)-1H-1,2,3-triazole; 5-Triazolylboronic acid pinacol ester; 5-Boronotriazole pinacol ester; 1203672-88-1
EINECS	Contact for details

Quality Control

Our 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-1,2,3-Triazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.