Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Imidazole CAS NO 1203671-64-0 is a high-purity, versatile boronic ester derivative of imidazole, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing imidazole heterocycles.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators.
• Material Science: Building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand & Catalyst Development: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organometallic catalysts.
• Chemical Biology & Proteomics: Useful in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Polymer Chemistry: Monomer for synthesizing functional polymers with tailored properties via cross-coupling polymerization.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Imidazole
CAS No.	1203671-64-0
Molecular Formula	C9H15BN2O2
Molecular Weight	194.04 g/mol
Synonyms	1H-Imidazole, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazole; Imidazole-5-boronic acid pinacol ester; 5-(Pinacolatoboryl)-1H-imidazole; 5-Imidazoleboronic acid pinacol ester; 5-Boronimidazole pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole
EINECS	Contact for details

Quality Control

Our 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Imidazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive applications like pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.