Description

1-(Piperidin-1-Yl)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Ethanone is a high-value, multi-functional chemical intermediate featuring a boronic ester-protected pyrazole moiety. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex carbon-carbon bonds. It is primarily sought after by pharmaceutical R&D and agrochemical laboratories for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring complex heterocyclic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Cross-Coupling Reactions: Specifically designed as a coupling partner in palladium-catalyzed Suzuki-Miyaura reactions to introduce the pyrazole-boronate functional group.
• Chemical Biology & Proteomics: Potential use in developing molecular probes and bioconjugation reagents due to its reactive handles.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and complex molecule construction in academic and industrial research settings.

Basic Information

Product Name	1-(Piperidin-1-Yl)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Ethanone
CAS No.	1203671-47-9
Molecular Formula	C16H26BN3O3
Molecular Weight	319.21 g/mol
Synonyms	1-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetyl]piperidine; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)-1-(piperidin-1-yl)ethanone; 1-(Piperidin-1-yl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]ethanone; 4-Pinacolatoboryl-1-[2-(1-piperidinyl)-2-oxoethyl]pyrazole; Pyrazole Boronic Acid Pinacol Ester Derivative
EINECS	Contact for details

Quality Control

Our production of 1-(Piperidin-1-Yl)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Ethanone adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; allow the sealed container to reach ambient temperature before opening to minimize moisture condensation and oxidative degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.