Description

(±)-1-(Trifluoromethyl)Cyclopentanamine Hydrochloride is a high-purity chiral amine building block, valued for its unique trifluoromethylated cyclopentane scaffold. This compound is essential for medicinal chemistry research and development, offering a versatile handle for modulating the physicochemical and metabolic properties of candidate molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and receptor interactions.
• Material Science Research: Explored as a monomer or additive for creating specialty polymers with unique surface properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	(±)-1-(Trifluoromethyl)Cyclopentanamine Hydrochloride
CAS No.	1202865-05-1
Molecular Formula	C6H11F3N • HCl
Molecular Weight	193.61 g/mol (Free base: 157.16 g/mol)
Synonyms	1-(Trifluoromethyl)cyclopentanamine hydrochloride (racemic); rac-1-(Trifluoromethyl)cyclopentan-1-amine hydrochloride; α-(Trifluoromethyl)cyclopentylamine hydrochloride; 1-Amino-1-(trifluoromethyl)cyclopentane hydrochloride; (±)-1-Amino-1-(trifluoromethyl)cyclopentane HCl; 1-Cyclopentyl-2,2,2-trifluoroethylamine hydrochloride; (RS)-1-(Trifluoromethyl)cyclopentanamine HCl
EINECS	Contact for details

Quality Control

Our (±)-1-(Trifluoromethyl)Cyclopentanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (50:50)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.