Description

tert-Butyl-n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Allyl]Carbamate is a high-value, protected amine boronic ester building block designed for advanced organic synthesis. This compound matters because it provides a versatile handle for Suzuki-Miyaura cross-coupling reactions while offering orthogonal protection for the amine functionality, enabling complex, multi-step synthetic sequences. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active molecules and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for coupling aryl/heteroaryl fragments.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boronic acid coupling steps.
• Material Science Research: Employed in the creation of novel organic electronic materials, polymers, and ligands where precise molecular architecture is critical.
• Peptide & Protein Modification: Facilitates the site-specific introduction of functional groups or labels into biomolecules via its reactive boronate and protected amine sites.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis to create diverse compound libraries for screening against biological targets.
• Cross-Coupling Reactions: Serves as a reliable partner in palladium-catalyzed Suzuki-Miyaura cross-coupling to form new carbon-carbon bonds.

Basic Information

Product Name	tert-Butyl-n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Allyl]Carbamate
CAS No.	1202794-01-1
Molecular Formula	C14H26BNO4
Molecular Weight	283.18 g/mol
Synonyms	Boc-Protected Allyl Boronic Acid Pinacol Ester; N-Boc-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)allylamine; tert-Butyl (2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allyl)carbamate; 2-(Boc-amino)allylboronic acid pinacol ester; N-(tert-Butoxycarbonyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allylamine; Allylboronic acid pinacol ester, N-Boc-protected; 1202794-01-1
EINECS	Contact for details

Quality Control

Our tert-Butyl-n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Allyl]Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.