Description

(E)-1-Ethoxyethene-2-Ylboronic Acid Pinacol Ester is a high-purity, advanced boronic ester building block designed for complex organic synthesis. This compound is valued for its role as a key coupling partner in transition-metal catalyzed cross-coupling reactions, enabling the efficient construction of carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel target molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between the vinylboron moiety and aryl or vinyl halides/triflates.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing functionalized ethene fragments.
• Agrochemical Compound Development: Employed in creating novel herbicides, fungicides, and insecticides with specific structural motifs.
• Material Science Research: Serves as a precursor for synthesizing organic electronic materials, such as components for OLEDs or conductive polymers.
• Complex Natural Product Synthesis: Facilitates the stereoselective introduction of ethoxyethene units in the total synthesis of complex natural products.
• Medicinal Chemistry & Drug Discovery: Enables rapid library synthesis for structure-activity relationship (SAR) studies in hit-to-lead optimization.

Basic Information

Product Name	(E)-1-Ethoxyethene-2-Ylboronic Acid Pinacol Ester
CAS No.	1201905-61-4
Molecular Formula	C₁₀H₁₉BO₃
Molecular Weight	198.07 g/mol
Synonyms	(E)-1-Ethoxyvinylboronic Acid Pinacol Ester; (E)-2-(1-Ethoxyvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; trans-1-Ethoxyethen-2-ylboronic Acid Pinacol Ester; (E)-1-Ethoxyvinyl-2-boronic Acid Pinacol Ester; (E)-Vinylboronic Acid Pinacol Ester, 1-Ethoxy Derivative; Boronic Acid, B-[(1E)-1-ethoxyethenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane Ester
EINECS	Contact for details

Quality Control

Our (E)-1-Ethoxyethene-2-Ylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is analyzed via NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity ((E)-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.