Description

1-{2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Ethyl}Imidazole is a high-purity, functionalized organoboron building block designed for advanced synthetic chemistry. This compound matters as a key intermediate in the synthesis of complex molecules, particularly for pharmaceutical research and materials science, due to its versatile imidazole and boronic ester functionalities. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality reagents for cross-coupling reactions and targeted molecular construction.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heteroaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aromatic and heterocyclic frameworks.
• Materials Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: The imidazole moiety can be utilized to develop novel ligands for metal catalysis or functional materials.
• Chemical Biology & Proteomics: Employed in the synthesis of probes and inhibitors that target enzymes or biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences and advanced materials sectors.

Basic Information

Product Name	1-{2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Ethyl}Imidazole
CAS No.	1201790-12-6
Molecular Formula	C₁₇H₂₃BN₂O₃
Molecular Weight	314.19 g/mol
Synonyms	2-[4-[2-(1H-Imidazol-1-yl)ethoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]ethyl]-1H-imidazole; 4,4,5,5-Tetramethyl-2-[4-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-1,3,2-dioxaborolane; 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)-1H-imidazole; Imidazole boronic ester pinacol derivative; 1-[2-(4-Boronophenoxy)ethyl]imidazole pinacol ester; (4-(2-(1H-Imidazol-1-yl)ethoxy)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-{2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Ethyl}Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.