Description

(3R,4S,5S)-3-(1-Ethylpropoxy)-4,5-Dihydroxy-1-Cyclohexene-1-Carboxylic Acid Ethyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional group array make it a valuable building block for the development of complex, biologically active molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a precursor or scaffold in drug discovery programs for hit-to-lead optimization and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Industrial R&D: Used in methodological development and catalysis research within organic chemistry laboratories.

Basic Information

Product Name	(3R,4S,5S)-3-(1-Ethylpropoxy)-4,5-Dihydroxy-1-Cyclohexene-1-Carboxylic Acid Ethyl Ester
CAS No.	1201685-71-3
Molecular Formula	C14H24O5
Molecular Weight	272.34 g/mol
Synonyms	Ethyl (3R,4S,5S)-3-(1-ethylpropoxy)-4,5-dihydroxycyclohex-1-ene-1-carboxylate; (3R,4S,5S)-3-(1-Ethylpropoxy)-4,5-dihydroxy-1-cyclohexene-1-carboxylic acid ethyl ester; 1-Cyclohexene-1-carboxylic acid, 3-(1-ethylpropoxy)-4,5-dihydroxy-, ethyl ester, (3R,4S,5S)-; Ethyl 3-(1-ethylpropoxy)-4,5-dihydroxycyclohex-1-enecarboxylate (stereoisomer).
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material with typical purities exceeding 97% (by HPLC), tailored to meet specific research and development requirements. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request. Production can be aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.