Description

2-(Methylamino)Thiazol-5-Ylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a critical step in constructing complex molecules for drug discovery and development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality synthetic reagents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and bioconjugates for target identification and validation.
• Academic & Contract Research: A valuable reagent for synthetic organic chemistry research in academic institutions and CROs (Contract Research Organizations).
• Custom Synthesis: A starting point for the custom manufacturing of complex, boronic acid-containing compounds for specialized applications.

Basic Information

Item	Detail
Product Name	2-(Methylamino)Thiazol-5-Ylboronic Acid Pinacol Ester
CAS No.	1201679-09-5
Molecular Formula	C11H19BN2O2S
Molecular Weight	254.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methyl-1,3-thiazol-2-amine; 2-(Methylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-Methylamino-thiazole-5-boronic acid pinacol ester; 2-Methylaminothiazole-5-boronic acid pinacol ester; N-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazol-2-amine
EINECS	Contact for details

Quality Control

Our 2-(Methylamino)Thiazol-5-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance in sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.