Description

Dioxaborolan-2-Yl)Pyridin-3-Yl)Oxazole CAS NO 1201644-46-3 is a specialized heterocyclic organic compound featuring a pyridinyl-oxazole core functionalized with a dioxaborolane group. This structure makes it a valuable high-purity synthetic intermediate and building block in advanced chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Cross-Coupling Reactions: Acts as a versatile organoboron reagent in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions for C-C bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Ligand Synthesis: Intermediate for the preparation of complex ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	Dioxaborolan-2-Yl)Pyridin-3-Yl)Oxazole
CAS No.	1201644-46-3
Molecular Formula	C13H12BN2O3
Molecular Weight	261.06 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(pyridin-3-yl)oxazole; 2-(3-Pyridinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole; (2-(Pyridin-3-yl)oxazol-4-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(3-pyridyl)oxazole; Oxazole-boronic acid pinacol ester derivative; Boro-oxazole intermediate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Dioxaborolan-2-Yl)Pyridin-3-Yl)Oxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.