Description

3-(1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic building block containing both an imidazole and a boronic ester pinacol group. This compound is essential for advanced organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and materials science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to construct novel herbicide and pesticide candidates through palladium-catalyzed coupling reactions.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and affinity tags due to the reactive imidazole and boronate ester functionalities.
• Ligand Synthesis: Useful for preparing complex polydentate ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A versatile reagent for methodological development and exploratory synthesis in academic and CRO laboratories.

Basic Information

Product Name	3-(1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1201644-45-2
Molecular Formula	C14H18BN3O2
Molecular Weight	271.13 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(1H-imidazol-1-yl)pyridine; 3-Imidazol-1-yl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine; 3-(1H-Imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(imidazol-1-yl)pyridine; Pyridine, 3-(1H-imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; CAS 1201644-45-2
EINECS	Contact for details

Quality Control

Our production of 3-(1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.