Description

n-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Cyclopropanecarboxamide is a high-value boronic ester derivative, a critical building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of biaryl and heterobiaryl structures, which are prevalent in medicinal chemistry.
• Agrochemical Research: Used in the development of new active ingredients for crop protection with enhanced efficacy.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and inhibitors for target identification and validation.
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic and industrial research laboratories.

Basic Information

Product Name	n-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Cyclopropanecarboxamide
CAS No.	1201644-41-8
Molecular Formula	C15H21BN2O3
Molecular Weight	288.15 g/mol
Synonyms	Cyclopropanecarboxamide, N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; 2-Pyridinecarboxamide, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropyl-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropylpicolinamide; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide, N-cyclopropyl-; CAS 1201644-41-8; Pinacol ester of (6-(cyclopropylcarbamoyl)pyridin-3-yl)boronic acid
EINECS	Contact for details

Quality Control

Our n-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Cyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for prolonged shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.