Description

2-Methoxyquinoline-6-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel quinoline-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by constructing complex heterocyclic scaffolds.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized in the preparation of molecular probes and bioconjugates for studying biological processes.
• Academic & Contract Research: A valuable reagent for method development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Detail
Product Name	2-Methoxyquinoline-6-Boronic Acid, Pinacol Ester
CAS No.	1201644-36-1
Molecular Formula	C₁₆H₂₀BNO₃
Molecular Weight	285.15 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxyquinoline; 2-Methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; 2-Methoxyquinolin-6-ylboronic acid pinacol ester; Quinoline-6-boronic acid, 2-methoxy-, pinacol ester; 1201644-36-1; 2-Methoxy-6-quinolineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxyquinoline-6-Boronic Acid, Pinacol Ester is manufactured and tested under strict quality management protocols. We ensure high lot-to-lot consistency through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.