Description

1-(Phenylsulfonyl)-1H-Pyrazol-4-Ylboronic Acid CAS NO 1201643-89-1 is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing heterocyclic cores prevalent in modern therapeutics.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, where its boronic acid functionality facilitates the creation of complex bioactive molecules.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Catalyst & Ligand Development: Acts as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	1-(Phenylsulfonyl)-1H-Pyrazol-4-Ylboronic Acid
CAS No.	1201643-89-1
Molecular Formula	C9H9BN2O2S
Molecular Weight	220.06 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(phenylsulfonyl)-1H-pyrazole; 1-(Benzenesulfonyl)-1H-pyrazol-4-ylboronic acid; 1H-Pyrazol-4-ylboronic acid, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)-1H-pyrazole-4-boronic acid; 1-(Phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; B-[1-(Phenylsulfonyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-1H-Pyrazol-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.