Description

1-Phenylpyrazole-4-Boronic Acid is a high-value boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, catalyst development, and functional material synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel organometallic catalysts and ligands for asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and inhibitors for studying biological pathways and protein function.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new chemical spaces in organic synthesis laboratories worldwide.

Basic Information

Product Name	1-Phenylpyrazole-4-Boronic Acid
CAS No.	1201643-70-0
Molecular Formula	C9H9BN2O2
Molecular Weight	188.00 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-phenyl-1H-pyrazole; 1-Phenyl-1H-pyrazole-4-boronic acid; 1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Phenyl-4-pyrazoleboronic acid; 1-Phenyl-4-boronopyrazole; 1-Phenylpyrazole-4-boronic acid pinacol ester; 4-Borono-1-phenylpyrazole
EINECS	Contact for details

Quality Control

Our 1-Phenylpyrazole-4-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.